Wednesday, 18 December 2013

Metabolic pathways

In biochemistrymetabolic pathways are series of chemical reactions occurring within a cell. In each pathway, a principal chemical is modified by a series of chemical reactionsEnzymescatalyze these reactions, and often require dietary minerals, vitamins, and other cofactors in order to function properly. Because of the many chemicals (a.k.a. "metabolites") that may be involved, metabolic pathways can be quite elaborate. In addition, numerous distinct pathways co-exist within a cell. This collection of pathways is called the metabolic network. Pathways are important to the maintenance of homeostasis within an organismCatabolic (break-down) and Anabolic (synthesis) pathways often work interdependently to create new biomolecules as the final end-products.
metabolic pathway involves the step-by-step modification of an initial molecule to form another product. The resulting product can be used in one of three ways:
  • To be used immediately,
  • To initiate another metabolic pathway, called a flux generating step
  • To be stored by the cell
A molecule called a substrate enters a metabolic pathway depending on the needs of the cell and the availability of the substrate. An increase in concentration of anabolic and catabolicintermediates and/or end-products may influence the metabolic rate for that particular pathway.

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